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Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Skrott, Zdenek; Mistrik, Martin; Andersen, Klaus Kaae; Friis, Søren; Majera, Dusana; Gursky, Jan; Ozdian, Tomas; Bartkova, Jirina; Turi, Zsofia; Moudry, Pavel; Kraus, Marianne; Michalova, Martina; Vaclavkova, Jana; Dzubak, Petr; Vrobel, Ivo; Pouckova, Pavla; Sedlacek, Jindrich; Miklovicova, Andrea; Kutt, Anne; Li, Jing; Mattova, Jana; Driessen, Christoph; Dou, Q Ping; Olsen, Jørgen; Hajduch, Marian; Cvek, Boris; Deshaies, Raymond J; Bartek, Jiri.
Afiliación
  • Skrott Z; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Mistrik M; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Andersen KK; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.
  • Friis S; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.
  • Majera D; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Gursky J; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Ozdian T; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Bartkova J; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.
  • Turi Z; Science for Life Laboratory, Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
  • Moudry P; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Kraus M; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Michalova M; Kantonsspital St Gallen, Department Oncology/Hematology, St Gallen, Switzerland.
  • Vaclavkova J; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Dzubak P; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Vrobel I; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Pouckova P; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Sedlacek J; Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
  • Miklovicova A; Department of Cell Biology & Genetics, Palacky University, Olomouc, Czech Republic.
  • Kutt A; Psychiatric Hospital, 785 01 Sternberk, Czech Republic.
  • Li J; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.
  • Mattova J; Division of Biology and Biological Engineering, Caltech, Pasadena, California 91125, USA.
  • Driessen C; Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University, 120 00 Prague 2, Czech Republic.
  • Dou QP; Kantonsspital St Gallen, Department Oncology/Hematology, St Gallen, Switzerland.
  • Olsen J; Barbara Ann Karmanos Cancer Institute and Department of Oncology, School of Medicine, Wayne State University, Detroit, Michigan, USA.
  • Hajduch M; School of Basic Medical Sciences, Affiliated Tumor Hospital of Guangzhou Medical University, Guangzhou 511436, China.
  • Cvek B; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.
  • Deshaies RJ; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Bartek J; Department of Cell Biology & Genetics, Palacky University, Olomouc, Czech Republic.
Nature ; 552(7684): 194-199, 2017 12 14.
Article en En | MEDLINE | ID: mdl-29211715

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Nucleares / Disulfiram / Disuasivos de Alcohol / Alcoholismo / Reposicionamiento de Medicamentos / Neoplasias / Antineoplásicos Límite: Adult / Animals / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: República Checa

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Nucleares / Disulfiram / Disuasivos de Alcohol / Alcoholismo / Reposicionamiento de Medicamentos / Neoplasias / Antineoplásicos Límite: Adult / Animals / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: República Checa