Recombinant protein of the first two ectodomains of cadherin 23 from erl mice shows impairment in Ca<sup>2+</sup>-dependent proteolysis protection.

Zhao, Mengmeng; Li, Ping; Xie, Yi; Liu, Xiang; Cheng, Lin; Liu, Tingyan; Kong, Lijun; Wang, Oumei; Han, Fengchan

Recombinant protein of the first two ectodomains of cadherin 23 from erl mice shows impairment in Ca²⁺-dependent proteolysis protection.

Zhao, Mengmeng; Li, Ping; Xie, Yi; Liu, Xiang; Cheng, Lin; Liu, Tingyan; Kong, Lijun; Wang, Oumei; Han, Fengchan.

Afiliación

Zhao M; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China.
Li P; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China.
Xie Y; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China.
Liu X; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China.
Cheng L; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China.
Liu T; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China.
Kong L; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China.
Wang O; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China. Electronic address: wangoumei@gmail.com.
Han F; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, 264003, PR China. Electronic address: hanfengc

Protein Expr Purif ; 147: 55-60, 2018 07.

Article en En | MEDLINE | ID: mdl-29486248

Asunto(s)

Cadherinas/metabolismo; Calcio/metabolismo; Pérdida Auditiva Sensorineural/metabolismo; Proteínas Recombinantes/metabolismo; Secuencia de Aminoácidos; Animales; Sitios de Unión/genética; Cadherinas/química; Cadherinas/genética; Pérdida Auditiva Sensorineural/genética; Cuerpos de Inclusión/química; Cuerpos de Inclusión/metabolismo; Ratones Endogámicos C57BL; Ratones Noqueados; Unión Proteica; Replegamiento Proteico; Estructura Secundaria de Proteína; Proteolisis; Proteínas Recombinantes/química; Homología de Secuencia de Aminoácido; Temperatura

Palabras clave

Cadherin 23; DFNB12; Ectodomains; Mutation; Protein expression; Tip link

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Recombinantes / Cadherinas / Calcio / Pérdida Auditiva Sensorineural Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Protein Expr Purif Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article

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