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A kinase-independent role for CDK8 in BCR-ABL1+ leukemia.
Menzl, Ingeborg; Zhang, Tinghu; Berger-Becvar, Angelika; Grausenburger, Reinhard; Heller, Gerwin; Prchal-Murphy, Michaela; Edlinger, Leo; Knab, Vanessa M; Uras, Iris Z; Grundschober, Eva; Bauer, Karin; Roth, Mareike; Skucha, Anna; Liu, Yao; Hatcher, John M; Liang, Yanke; Kwiatkowski, Nicholas P; Fux, Daniela; Hoelbl-Kovacic, Andrea; Kubicek, Stefan; Melo, Junia V; Valent, Peter; Weichhart, Thomas; Grebien, Florian; Zuber, Johannes; Gray, Nathanael S; Sexl, Veronika.
Afiliación
  • Menzl I; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Zhang T; Department of Cancer Biology, Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Berger-Becvar A; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Grausenburger R; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Heller G; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Prchal-Murphy M; Department of Medicine I, Medical University of Vienna, Vienna, Austria.
  • Edlinger L; Comprehensive Cancer Center, Vienna, Austria.
  • Knab VM; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Uras IZ; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Grundschober E; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Bauer K; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Roth M; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Skucha A; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.
  • Liu Y; Research Institute of Molecular Pathology, Campus-Vienna-Biocenter 1, Vienna, Austria.
  • Hatcher JM; Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria.
  • Liang Y; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
  • Kwiatkowski NP; Department of Cancer Biology, Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Fux D; Department of Cancer Biology, Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Hoelbl-Kovacic A; Department of Cancer Biology, Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Kubicek S; Department of Cancer Biology, Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Melo JV; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Valent P; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.
  • Weichhart T; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
  • Grebien F; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, South Australia, 5005, Australia.
  • Zuber J; Department of Hematology, Imperial College London, Kensington, London, SW7 2AZ, UK.
  • Gray NS; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.
  • Sexl V; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
Nat Commun ; 10(1): 4741, 2019 10 18.
Article en En | MEDLINE | ID: mdl-31628323
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Proteínas de Fusión bcr-abl / Modelos Animales de Enfermedad / Quinasa 8 Dependiente de Ciclina Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Austria
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Proteínas de Fusión bcr-abl / Modelos Animales de Enfermedad / Quinasa 8 Dependiente de Ciclina Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Austria