Destabilization of FoxM1 and Inhibition of Topoisomerase I Contribute to Cytotoxicity of Prenylated Xanthones Isolated from Metaxya rostrata.

Mittermair, Eva; Schueffl, Hemma; Heffeter, Petra; Krenn, Liselotte; Marian, Brigitte

Mittermair, Eva; Schueffl, Hemma; Heffeter, Petra; Krenn, Liselotte; Marian, Brigitte.

Afiliación

Mittermair E; Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria.
Schueffl H; Department of Pharmacognosy, University of Vienna, Vienna, Austria.
Heffeter P; Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria.
Krenn L; Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria.
Marian B; Department of Pharmacognosy, University of Vienna, Vienna, Austria.

Planta Med ; 86(15): 1073-1079, 2020 Oct.

Article en En | MEDLINE | ID: mdl-32023632

Asunto(s)

ADN-Topoisomerasas de Tipo I; Xantonas; Células CACO-2; Puntos de Control del Ciclo Celular; Línea Celular Tumoral; Helechos/química; Proteína Forkhead Box M1/genética; Humanos; Xantonas/toxicidad

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN-Topoisomerasas de Tipo I / Xantonas Límite: Humans Idioma: En Revista: Planta Med Año: 2020 Tipo del documento: Article País de afiliación: Austria

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