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Drug Sensitivity and Allele Specificity of First-Line Osimertinib Resistance EGFR Mutations.
Starrett, Jacqueline H; Guernet, Alexis A; Cuomo, Maria Emanuela; Poels, Kamrine E; van Alderwerelt van Rosenburgh, Iris K; Nagelberg, Amy; Farnsworth, Dylan; Price, Kristin S; Khan, Hina; Ashtekar, Kumar Dilip; Gaefele, Mmaserame; Ayeni, Deborah; Stewart, Tyler F; Kuhlmann, Alexandra; Kaech, Susan M; Unni, Arun M; Homer, Robert; Lockwood, William W; Michor, Franziska; Goldberg, Sarah B; Lemmon, Mark A; Smith, Paul D; Cross, Darren A E; Politi, Katerina.
Afiliación
  • Starrett JH; Department of Pathology, Yale School of Medicine, New Haven, Connecticut.
  • Guernet AA; Discovery Biology, Discovery Sciences, R&D Biopharmaceuticals, AstraZeneca, Cambridge, United Kingdom.
  • Cuomo ME; Discovery Biology, Discovery Sciences, R&D Biopharmaceuticals, AstraZeneca, Cambridge, United Kingdom.
  • Poels KE; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; and Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • van Alderwerelt van Rosenburgh IK; Department of Pharmacology, Yale School of Medicine, New Haven, Connecticut.
  • Nagelberg A; Cancer Biology Institute, Yale School of Medicine, New Haven, Connecticut.
  • Farnsworth D; Department of Integrative Oncology, British Columbia Cancer and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Price KS; Department of Integrative Oncology, British Columbia Cancer and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Khan H; Guardant Health, Redwood City, California.
  • Ashtekar KD; Warren Alpert Medical School, Brown University, Providence, Rhode Island; and Lifespan Cancer Institute, Providence, Rhode Island.
  • Gaefele M; Department of Pharmacology, Yale School of Medicine, New Haven, Connecticut.
  • Ayeni D; Cancer Biology Institute, Yale School of Medicine, New Haven, Connecticut.
  • Stewart TF; Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.
  • Kuhlmann A; Department of Pathology, Yale School of Medicine, New Haven, Connecticut.
  • Kaech SM; Department of Medicine (Section of Medical Oncology), Yale School of Medicine, New Haven, Connecticut.
  • Unni AM; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut.
  • Homer R; NOMIS Center for Immunobiology and Microbial Pathogenesis, The Salk Institute, La Jolla, California.
  • Lockwood WW; Meyer Cancer Center, Weill Cornell Medicine, New York, New York.
  • Michor F; Department of Pathology, Yale School of Medicine, New Haven, Connecticut.
  • Goldberg SB; Pathology and Laboratory Medicine Service, VA CT HealthCare System, West Haven, Connecticut.
  • Lemmon MA; Department of Integrative Oncology, British Columbia Cancer and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Smith PD; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; and Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Cross DAE; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts; Center for Cancer Evolution, Dana-Farber Cancer Institute, Boston, Massachusetts; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts; and The Ludwig Center at Harvard, Boston, Massachusetts.
  • Politi K; Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.
Cancer Res ; 80(10): 2017-2030, 2020 05 15.
Article en En | MEDLINE | ID: mdl-32193290

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Acrilamidas / Adenocarcinoma / Resistencia a Antineoplásicos / Inhibidores de Proteínas Quinasas / Compuestos de Anilina / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Female / Humans / Middle aged Idioma: En Revista: Cancer Res Año: 2020 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Acrilamidas / Adenocarcinoma / Resistencia a Antineoplásicos / Inhibidores de Proteínas Quinasas / Compuestos de Anilina / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Female / Humans / Middle aged Idioma: En Revista: Cancer Res Año: 2020 Tipo del documento: Article