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Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial.
Ranganath, Lakshminarayan R; Psarelli, Eftychia Eirini; Arnoux, Jean-Baptiste; Braconi, Daniela; Briggs, Michael; Bröijersén, Anders; Loftus, Nadia; Bygott, Helen; Cox, Trevor F; Davison, Andrew S; Dillon, Jane P; Fisher, Michael; FitzGerald, Richard; Genovese, Federica; Glasova, Helena; Hall, Anthony K; Hughes, Andrew T; Hughes, Juliette H; Imrich, Richard; Jarvis, Jonathan C; Khedr, Milad; Laan, Dinny; Le Quan Sang, Kim-Hanh; Luangrath, Emily; Lukácová, Ol'ga; Milan, Anna M; Mistry, Alpesh; Mlynáriková, Vanda; Norman, Brendan P; Olsson, Birgitta; Rhodes, Nicholas P; Rovenský, Jozef; Rudebeck, Mattias; Santucci, Annalisa; Shweihdi, Ella; Scott, Ciarán; Sedláková, Jana; Sireau, Nicolas; Stancík, Roman; Szamosi, Johan; Taylor, Sophie; van Kan, Christa; Vinjamuri, Sobhan; Vrtíková, Eva; Webb, Chris; West, Elizabeth; Zánová, Elizabeth; Zatkova, Andrea; Gallagher, James A.
Afiliación
  • Ranganath LR; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK. Electronic address: lrang@liv.ac.uk.
  • Psarelli EE; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK.
  • Arnoux JB; Hôpital Necker-Enfants Malades, Paris, France.
  • Braconi D; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
  • Briggs M; Department of Ophthalmology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Bröijersén A; Swedish Orphan Biovitrum, Stockholm, Sweden.
  • Loftus N; Department of Physiotherapy, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Bygott H; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Cox TF; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK.
  • Davison AS; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Dillon JP; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
  • Fisher M; Department of Cardiology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • FitzGerald R; Department of Clinical Pharmacology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Genovese F; Nordic Bioscience, Herlev, Denmark.
  • Glasova H; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia; Institute of Pharmacology and Clinical Pharmacology, Slovak Medical University, Bratislava, Slovakia.
  • Hall AK; Cudos, Hoofddorp, Netherlands.
  • Hughes AT; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Hughes JH; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
  • Imrich R; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia; National Institute of Rheumatic Diseases, Piest'any, Slovakia.
  • Jarvis JC; School of Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK.
  • Khedr M; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Laan D; PSR Group, Hoofddorp, Netherlands.
  • Le Quan Sang KH; Hôpital Necker-Enfants Malades, Paris, France.
  • Luangrath E; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Lukácová O; National Institute of Rheumatic Diseases, Piest'any, Slovakia.
  • Milan AM; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Mistry A; Department of Radiology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Mlynáriková V; National Institute of Rheumatic Diseases, Piest'any, Slovakia.
  • Norman BP; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
  • Olsson B; Swedish Orphan Biovitrum, Stockholm, Sweden.
  • Rhodes NP; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
  • Rovenský J; National Institute of Rheumatic Diseases, Piest'any, Slovakia.
  • Rudebeck M; Swedish Orphan Biovitrum, Stockholm, Sweden.
  • Santucci A; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
  • Shweihdi E; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Scott C; AKU Society, Cambridge, UK.
  • Sedláková J; National Institute of Rheumatic Diseases, Piest'any, Slovakia.
  • Sireau N; AKU Society, Cambridge, UK.
  • Stancík R; National Institute of Rheumatic Diseases, Piest'any, Slovakia.
  • Szamosi J; Swedish Orphan Biovitrum, Stockholm, Sweden.
  • Taylor S; Department of Physiotherapy, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • van Kan C; PSR Group, Hoofddorp, Netherlands.
  • Vinjamuri S; Department of Nuclear Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Vrtíková E; National Institute of Rheumatic Diseases, Piest'any, Slovakia.
  • Webb C; Department of Ear, Nose and Throat, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • West E; Department of Dermatology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
  • Zánová E; National Institute of Rheumatic Diseases, Piest'any, Slovakia.
  • Zatkova A; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
  • Gallagher JA; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
Lancet Diabetes Endocrinol ; 8(9): 762-772, 2020 09.
Article en En | MEDLINE | ID: mdl-32822600
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ciclohexanonas / Internacionalidad / Alcaptonuria / Inhibidores Enzimáticos / Nitrobenzoatos Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Diabetes Endocrinol Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ciclohexanonas / Internacionalidad / Alcaptonuria / Inhibidores Enzimáticos / Nitrobenzoatos Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Diabetes Endocrinol Año: 2020 Tipo del documento: Article