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A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease.
Douglas, Lisa E J; Reihill, James A; Ho, Melisa W Y; Axten, Jeffrey M; Campobasso, Nino; Schneck, Jessica L; Rendina, Alan R; Wilcoxen, Keith M; Martin, S Lorraine.
Afiliación
  • Douglas LEJ; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.
  • Reihill JA; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.
  • Ho MWY; GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Axten JM; GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Campobasso N; GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Schneck JL; GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Rendina AR; GlaxoSmithKline Research and Development, Collegeville, PA 19426, USA.
  • Wilcoxen KM; Boston Pharmaceuticals, Cambridge, MA 02142, USA.
  • Martin SL; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. Electronic address: l.martin@qub.ac.uk.
Cell Chem Biol ; 29(6): 947-957.e8, 2022 06 16.
Article en En | MEDLINE | ID: mdl-35202587

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fibrosis Quística / Furina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fibrosis Quística / Furina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido