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2-Methoxy-5((3,4,5-trimethosyphenyl) seleninyl) phenol causes G2/M cell cycle arrest and apoptosis in NSCLC cells through mitochondrial apoptotic pathway and MDM2 inhibition.
Liu, Yang; Meng, Yuting; Bian, Jiang; Liu, Bolin; Li, Xuefen; Guan, Qi; Li, Zengqiang; Zhang, Weige; Wu, Yingliang; Zuo, Daiying.
Afiliación
  • Liu Y; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China.
  • Meng Y; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China.
  • Bian J; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China.
  • Liu B; College of Pharmacy, China Medical University, Shenyang, China.
  • Li X; Department of Pharmacy, Inner Mongolia Hospital of Traditional Chinese Medicine, Hohhot, China.
  • Guan Q; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
  • Li Z; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China.
  • Zhang W; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
  • Wu Y; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China.
  • Zuo D; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China.
J Biochem Mol Toxicol ; 36(7): e23066, 2022 Jul.
Article en En | MEDLINE | ID: mdl-35384151
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Proteínas Proto-Oncogénicas c-mdm2 / Neoplasias Pulmonares Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: J Biochem Mol Toxicol Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Proteínas Proto-Oncogénicas c-mdm2 / Neoplasias Pulmonares Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: J Biochem Mol Toxicol Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China