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Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation.
Klasfauseweh, Tabea; Israel, Mathilde R; Ragnarsson, Lotten; Cox, James J; Durek, Thomas; Carter, David A; Leffler, Andreas; Vetter, Irina; Deuis, Jennifer R.
Afiliación
  • Klasfauseweh T; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, 4072, Australia; Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, 30625, Hannover, Germany.
  • Israel MR; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, 4072, Australia; Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE1 1UL, UK.
  • Ragnarsson L; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, 4072, Australia.
  • Cox JJ; Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London, WC1E 6BT, UK.
  • Durek T; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, 4072, Australia.
  • Carter DA; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, 4072, Australia.
  • Leffler A; Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, 30625, Hannover, Germany.
  • Vetter I; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, 4072, Australia; School of Pharmacy, The University of Queensland, Woolloongabba, QLD, 4102, Australia. Electronic address: i.vetter@uq.edu.au.
  • Deuis JR; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, 4072, Australia. Electronic address: j.deuis@uq.edu.au.
Eur J Pharmacol ; 925: 175013, 2022 Jun 15.
Article en En | MEDLINE | ID: mdl-35537491
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Anestésicos Locales / Lidocaína Límite: Humans Idioma: En Revista: Eur J Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Anestésicos Locales / Lidocaína Límite: Humans Idioma: En Revista: Eur J Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Alemania