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A novel strategy for delivering Niemann-Pick type C2 proteins across the blood-brain barrier using the brain endothelial-specific AAV-BR1 virus.
Rasmussen, Charlotte Laurfelt Munch; Hede, Eva; Routhe, Lisa Juul; Körbelin, Jakob; Helgudottir, Steinunn Sara; Thomsen, Louiza Bohn; Schwaninger, Markus; Burkhart, Annette; Moos, Torben.
Afiliación
  • Rasmussen CLM; Neurobiology Research and Drug Delivery, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
  • Hede E; Neurobiology Research and Drug Delivery, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
  • Routhe LJ; Neurobiology Research and Drug Delivery, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
  • Körbelin J; Department of Oncology, Hematology and Bone Marrow Transplantation, University Medical Center, Hamburg, Germany.
  • Helgudottir SS; Neurobiology Research and Drug Delivery, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
  • Thomsen LB; Neurobiology Research and Drug Delivery, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
  • Schwaninger M; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany.
  • Burkhart A; Neurobiology Research and Drug Delivery, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
  • Moos T; Neurobiology Research and Drug Delivery, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
J Neurochem ; 164(1): 6-28, 2023 01.
Article en En | MEDLINE | ID: mdl-35554935
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Barrera Hematoencefálica / Enfermedad de Niemann-Pick Tipo C Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neurochem Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Barrera Hematoencefálica / Enfermedad de Niemann-Pick Tipo C Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neurochem Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca