Nueva variante en el polimorfismo del intrón 4 de la enzima Oxido Nítrico Sintasa endotelial (eNOS) / A new variant of the polymorphism in the fourth intron from the endothelial nitric oxide synthase enzyme
Prensa méd. argent
; 95(5): 291-294, jul. 2008. ilus
Article
em Es
| LILACS
| ID: lil-522001
Biblioteca responsável:
AR392.1
ABSTRACT
Nitric oxide (NO) derived from endothelial Nitric Oxide Synthase enzyme (eNOS) is an important mediator of the vascular function. Various polymorphisms have been described for the eNOS gene that has effects on its expression. One of the most studied markers in the eNOS gen is located in the fourth intron and is characterized by the presence of a variable number of tandemly repeated sequence of 27 base pairs. In this work we report the existence and the sequence of a new variant for these polymorphism and we hypothestize its potential role in the regulation of NO productition by eNOS.
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Polimorfismo Genético
/
Doença da Artéria Coronariana
/
Marcadores Genéticos
/
Isquemia Miocárdica
/
Sequências de Repetição em Tandem
/
MicroRNAs
/
Alelos
/
Óxido Nítrico Sintase Tipo III
Limite:
Humans
Idioma:
Es
Revista:
Prensa méd. argent
Assunto da revista:
MEDICINA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Argentina