Association between mucositis severity and vancomycin-resistant enterococcal bloodstream infection in hospitalized cancer patients.
Infect Control Hosp Epidemiol
; 20(10): 660-3, 1999 Oct.
Article
em En
| MEDLINE
| ID: mdl-10530642
ABSTRACT
OBJECTIVE:
To determine the role of mucositis severity in the development of vancomycin-resistant enterococcal (VRE) bloodstream infection (BSI).SETTING:
A tertiary-care university medical center.PARTICIPANTS:
Hematology-oncology-unit inpatients.DESIGN:
Patients with VRE BSI (case-patients) were compared with VRE-colonized (control) patients from September 1994 through August 1997. Oral mucositis severity was recorded on the day of VRE BSI for case-patients and on hospital day 22 (median day of hospitalization of case-patient VRE BSI) for controls. There were 19 case-patients and 31 controls.RESULTS:
In univariate analysis, case-patients were significantly more likely than controls to have a higher mucositis severity score, diarrhea, or a higher severity of illness score. In multivariate analysis, only mucositis remained as an independent risk factor, and increasing mucositis score was significantly associated with VRE BSI.CONCLUSIONS:
Mucositis severity was independently associated with an increasing risk for VRE BSI. Interventions to alter mucositis severity may help to prevent VRE BSI in hospitalized cancer patients.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estomatite
/
Infecções por Bactérias Gram-Positivas
/
Enterococcus
/
Bacteriemia
/
Resistência a Vancomicina
/
Neoplasias
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Infect Control Hosp Epidemiol
Assunto da revista:
DOENCAS TRANSMISSIVEIS
/
ENFERMAGEM
/
EPIDEMIOLOGIA
/
HOSPITAIS
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Estados Unidos