Testosterone improves rehabilitation outcomes in ill older men.
J Am Geriatr Soc
; 48(5): 550-3, 2000 May.
Article
em En
| MEDLINE
| ID: mdl-10811549
ABSTRACT
OBJECTIVES:
To determine whether testosterone supplementation improves rehabilitation outcomes in ill older men.DESIGN:
A randomized, placebo-controlled, double-blind study.SETTING:
A Geriatric Evaluation and Management (GEM) unit based at a university- affiliated Veterans Affairs Medical Center.PARTICIPANTS:
Fifteen men aged 65 to 90 years admitted to the GEM for rehabilitation. INTERVENTION Subjects were randomized to receive weekly intramuscular injections with testosterone enanthate 100 mg or placebo. MEASUREMENTS Task-specific performance using the Functional Independence Measure (FIM) and grip strength was measured at the onset of the study and at the time of discharge from the GEM.RESULTS:
At baseline, FIM scores were similar between the placebo and the testosterone group (73.7 vs 70.7, P = .637), as was grip strength (49.7 vs 55.3 pounds, P = .555). At discharge from the GEM, testosterone-treated patients had improved FIM scores compared with baseline (93.6 vs 70.7; P = .012) and grip strength (68.7 vs 55.3 pounds; P = .033). In the placebo group there was no significant improvement of FIM scores compared with baseline (78.0 versus 73.7; P = .686) or of grip strength (48.9 vs 49.7 pounds; P = .686).CONCLUSIONS:
Testosterone supplementation may improve rehabilitation outcomes in ill older men.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reabilitação
/
Testosterona
/
Atividades Cotidianas
Tipo de estudo:
Clinical_trials
Limite:
Aged
/
Aged80
/
Humans
/
Male
Idioma:
En
Revista:
J Am Geriatr Soc
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Estados Unidos