[Effect of "micronized" C60 fullerene on the microbial growth in vitro]. / Effet du fullerène C60 "micronisé" sur la croissance microbienne in vitro.
Ann Pharm Fr
; 58(3): 170-5, 2000 May.
Article
em Fr
| MEDLINE
| ID: mdl-10844277
ABSTRACT
The effect of C60 "micronized fullerene was tested by a manual and automatised (Analyzer Bioscreen C(R)) micromethod on the microbial growth of 22 collection strains E. coli (5), P. aeruginosa (2), S. Typhimurium (6), S. aureus (2), L. monocytogenes (2), E. hirae (1), B. cereus (1), B. subtilis (1), B. pumilus (1) et C. albicans (1). No effect on microbial growth was observed with C60 "micronized fullerene (43.2 microg/ml) on all strains studied no difference was found with doubling time, slope and growth rate constant. The results of cytotoxicity obtained with animal models or in vitro cultures as human monocyte, leukocyte or macrophage confirm the absence of effect of C60 fullerene at a concentration compatible with microbial or biological models. This study is included in research program headed "Therapeutics perspectives of fullerenes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bactérias
/
Carbono
/
Fulerenos
Tipo de estudo:
Guideline
/
Prognostic_studies
Idioma:
Fr
Revista:
Ann Pharm Fr
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
França