Biotransformation of a C-glycosylflavone, abrusin 2''-O-beta-D-apioside, by human intestinal bacteria.
Chem Pharm Bull (Tokyo)
; 48(8): 1239-41, 2000 Aug.
Article
em En
| MEDLINE
| ID: mdl-10959599
ABSTRACT
After anaerobic incubation of abrusin 2''-O-beta-D-apioside (1) with a human fecal suspension, five metabolites were isolated and identified as abrusin (2), 1-(2',6'-dihydroxy-3',4'-dimethoxyphenyl)-3-(4''-hydroxyphenyl)propan-1- one (5), 5,6-dimethoxybenzene-1,3-diol (6), 3-(4'-hydroxyphenyl)propionic acid (7) and 3-phenylpropionic acid (8). However, methyl ether derivatives of abrusin (4'-O-methylabrusin and 4'-O-, 5-O-dimethylabrusin) resisted degradation under the same conditions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Flavonoides
/
Glicosídeos
/
Intestinos
Limite:
Humans
Idioma:
En
Revista:
Chem Pharm Bull (Tokyo)
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Japão