[Upper digestive tract findings in elderly patients with iron-deficiency anemia. A comparison between users and non-users of non-steroidal anti-inflammatory drugs]. / Patología digestiva alta en pacientes de edad avanzada con anemia ferropénica: comparación entre usuarios y no usuarios de anti-inflamatorios no esteroideos.
An Med Interna
; 18(7): 357-60, 2001 Jul.
Article
em Es
| MEDLINE
| ID: mdl-11534419
ABSTRACT
BACKGROUND:
Iron-deficiency anemia is common in the elderly. Chronic upper gastrointestinal bleeding is its most frequent cause. The use of non-steroidal antinflammatory drugs (NSAID) is common in older people. Gastrointestinal complications of NSAID may be also more frequent among the elderly.AIMS:
The study was aimed to evaluate if a history of regular NSAID use in elderly patients with iron-deficiency anemia is associated to characteristic findings on esophagogastroduodenoscopy. MATERIALS ANDMETHODS:
A total of 91 patients (40% of males and 60% females) older than 65 years (mean age 77 years, range 65-90 years) entered the study. All of them had been admitted to our Hospital for study of iron-deficiency anemia. Thirty-eight patients were regular users of NSAID. Esophagogastroduodenoscopy was performed in all patients.RESULTS:
The prevalences of peptic ulcer, erosive gastritis/duodenitis, and esophagitis were similar in NSAID users and non-users (13 vs 11%, 18 vs 15%, and 26 vs 26%, respectively). A trend to a higher prevalence of gastric adenocarcinoma was observed the group of NSAID non-users (8% vs 23%, p = 0.05). Esophagogastroduodenoscopy was entirely normal in 39% of NSAID users and 34% of NSAID non-users.CONCLUSIONS:
Upper gastrointestinal lesions in elderly patients with iron-deficiency anemia are similar in NSAID users and non-users, with the exception of gastric adenocarcinoma which can be more common in NSAID non-users.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anti-Inflamatórios não Esteroides
/
Anemia Ferropriva
/
Gastroenteropatias
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
An Med Interna
Assunto da revista:
MEDICINA INTERNA
Ano de publicação:
2001
Tipo de documento:
Article