Neuronal plasticity and cellular immunity: shared molecular mechanisms.
Curr Opin Neurobiol
; 11(5): 568-78, 2001 Oct.
Article
em En
| MEDLINE
| ID: mdl-11595490
ABSTRACT
It is becoming evident that neurons express an unusual number of molecules that were originally thought to be specific to immune functions. One such molecule, class I major histocompatibility complex, is required in the activity-dependent refinement and plasticity of connections in the developing and adult central nervous system, demonstrating that molecules can perform critical roles in both systems. Recent studies reveal striking parallels between cellular signaling mechanisms in the immune and nervous systems that may provide unexpected insights into the development, function, and diseases of both systems.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imunidade Celular
/
Plasticidade Neuronal
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Opin Neurobiol
Assunto da revista:
BIOLOGIA
/
NEUROLOGIA
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Estados Unidos