A novel sample holder allowing atomic force microscopy on transmission electron microscopy specimen grids: repetitive, direct correlation between AFM and TEM images.
J Microsc
; 205(Pt 2): 205-8, 2002 Feb.
Article
em En
| MEDLINE
| ID: mdl-11879435
ABSTRACT
A novel sample holder that allows atomic force microscopy (AFM) to be performed on transmission electron microscope (TEM) grids is described. Consequently, AFM and TEM images were repeatedly obtained on exactly the same sample area. For both techniques, a thin carbon film was used as the imaging substrate. Although these techniques have been previously used in conjunction, AFM and TEM images on exactly the same area have not been repeatedly obtained for any system. Correlation of AFM and TEM images is useful for work where the three-dimensional topographical information provided by the AFM could be used to better interpret the two-dimensional images provided by the TEM and vice versa. To demonstrate the applicability of such correlation, new results pertaining to a fibrillar collagen system are summarized.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microscopia de Força Atômica
/
Colágenos Fibrilares
Tipo de estudo:
Evaluation_studies
Limite:
Humans
Idioma:
En
Revista:
J Microsc
Ano de publicação:
2002
Tipo de documento:
Article