Expression of cardiac neural crest and heart genes isolated by modified differential display.
Gene Expr Patterns
; 3(4): 407-11, 2003 Aug.
Article
em En
| MEDLINE
| ID: mdl-12915302
ABSTRACT
The invasion of the cardiac neural crest (CNC) into the outflow tract (OFT) and subsequent outflow tract septation are critical events during vertebrate heart development. We have performed four modified differential display screens in the chick embryo to identify genes that may be involved in CNC, OFT, secondary heart field, and heart development. The screens included differential display of RNA isolated from three different axial segments containing premigratory cranial neural crest cells; of RNA from distal outflow tract, proximal outflow tract, and atrioventricular tissue of embryonic chick hearts; and of RNA isolated from left and right cranial tissues, including the early heart fields. These screens have resulted in the identification of the five cDNA clones presented here, which are expressed in the cardiac neural crest, outflow tract and developing heart in patterns that are unique in heart development.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Regulação da Expressão Gênica no Desenvolvimento
/
Coração
/
Miocárdio
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Crista Neural
Limite:
Animals
Idioma:
En
Revista:
Gene Expr Patterns
Assunto da revista:
BIOLOGIA MOLECULAR
/
CEREBRO
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Estados Unidos