DNA topoisomerases.

Hsieh, T S

DNA topoisomerases.

Hsieh, T S.

Afiliação

Hsieh TS; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710.

Curr Opin Cell Biol ; 4(3): 396-400, 1992 Jun.

Article em En | MEDLINE | ID: mdl-1323315

ABSTRACT

ABSTRACT

DNA topoisomerases play an important role in regulating DNA structure, thus affecting many aspects of chromosome function inside cells. Recent progress in this field raises exciting questions regarding the distinct and critical functions of multiple topoisomerases, and the roles of DNA topoisomerases in the processes of chromosome condensation, decondensation, and segregation.

Assuntos

DNA Topoisomerases Tipo I/genética; Antineoplásicos/farmacologia; Bactérias/enzimologia; Bactérias/genética; Cromossomos/enzimologia; Humanos; Isoenzimas/genética; Família Multigênica; Inibidores da Topoisomerase I; Leveduras/enzimologia; Leveduras/genética

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Topoisomerases Tipo I Limite: Humans Idioma: En Revista: Curr Opin Cell Biol Ano de publicação: 1992 Tipo de documento: Article

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