The 38-kDa protein of Mycobacterium tuberculosis: a review.
J Infect Dis
; 166(4): 874-84, 1992 Oct.
Article
em En
| MEDLINE
| ID: mdl-1527425
ABSTRACT
This review illustrates that the 38-kDa protein is one of the most important antigens of Mycobacterium tuberculosis. It is actively secreted but partly attached to the surface of the mycobacterial cell by a lipid tail that may also be responsible for binding of carbohydrate to the protein. It is a major constituent of M. tuberculosis culture fluid after growth on the synthetic Sauton medium and occurs in bacille Calmette-Guérin in far lower concentrations. The protein induces B and T cell responses with high specificity for infection with M. tuberculosis and is a prime candidate for development of new diagnostic reagents for tuberculosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tuberculina
/
Mycobacterium tuberculosis
/
Antígenos de Bactérias
Limite:
Animals
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Noruega