The effects of somatostatin in the polycystic ovary syndrome.
J Obstet Gynaecol
; 17(6): 560-4, 1997 Nov.
Article
em En
| MEDLINE
| ID: mdl-15511959
Eighteen obese women (body mass index 30 +/- 6.1 kg/m2) with hyperinsulinaemia and with the polycystic ovary syndrome took octreotide at the dose of 100 mug s.c. The effect of the drug was assessed on plasma levels of gonadotropins luteinising hormone (LH), follicle stimulating hormone (FSH), of insulin, insulin-like growth factor-1 (IGF-1), androstenedione, testosterone, dehydroepiandrosterone sulphate (DHEAS), sex hormone binding globulin (SHBG) and insulin-like growth factor-binding protein-3 (IGFBP-3). Octreotide significantly reduced LH (31.8%), insulin (52%), IGF-1 (14%), androstenedione (22.6%) and testosterone (20%) and increased IGFBP-3 (25%).
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01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Obstet Gynaecol
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Itália