[Genetic causes of male infertility]. / Genetische Ursachen der männlichen Infertilität.
Verh Dtsch Ges Pathol
; 88: 130-5, 2004.
Article
em De
| MEDLINE
| ID: mdl-16892543
ABSTRACT
7% of all human males suffer from infertility. In at least 10% of these males infertility is due to genetic causes. Because modern reproduction techniques like ICSI (intracytoplasmic sperm injection) can help the couples to overcome infertility, it is mandatory to analyze underlying genetic causes of male infertility. If infertility in a male is due to a genetic defect, the risk of the respective couple for abortuses or malformed children is increased. The main and relevant causes for male infertility known to day are numerical and structural chromosomal aberrations, meiotic defects, microdeletions in the region q11.21-23 of the Y-chromosome, mutations in the gene for cystic fibrosis and genetically determined syndromes in which infertility is a symptom. The present knowledge concerning these genetic causes of male infertility is pointed out.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infertilidade Masculina
Tipo de estudo:
Etiology_studies
Limite:
Female
/
Humans
/
Male
Idioma:
De
Revista:
Verh Dtsch Ges Pathol
Ano de publicação:
2004
Tipo de documento:
Article