Twenty-three novel alleles increase diversity at the HLA-C locus.
Tissue Antigens
; 71(6): 560-3, 2008 Jun.
Article
em En
| MEDLINE
| ID: mdl-18380775
ABSTRACT
Twenty-three novel HLA-C alleles are described. Nine of the new alleles are single-nucleotide substitutions from their most homologous allele of which seven result in amino acid changes (Cw*0327, *0508, *0514, *0613, *0735, *0739 and *1517) and two are silent substitutions (Cw*030305 and *070107). The remaining 14 alleles (Cw*0113, *0207, *0212, *0216, *0318, *0411, *0417, *0512, *0722, *0733N, *1216, *1218, *1515 and *1607) differ from their most similar alleles by 2-4 nucleotide substitutions that result in 1-3 amino acid differences.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antígenos HLA-C
/
Substituição de Aminoácidos
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Locos de Características Quantitativas
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Alelos
Limite:
Humans
Idioma:
En
Revista:
Tissue Antigens
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos