Fagraldehyde, a secoiridoid isolated from Fagraea fragrans.
J Nat Prod
; 71(12): 2038-40, 2008 Dec.
Article
em En
| MEDLINE
| ID: mdl-19053508
ABSTRACT
A secoiridoid aglycone with an atypical skeleton, named fagraldehyde (1), together with several known secoiridoids (gentiopicroside (2), sweroside (3), and swertiamarin (4)) were isolated from the bark and leaves of Fagraea fragrans collected in Cambodia. The conformations of 1 were evaluated on the basis of molecular modeling and NOESY correlations. A hypothetical biogenesis of fagraldehyde was proposed to explain the unusual skeleton. Compound 1 was weakly active in vitro against Plasmodium falciparum.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmodium falciparum
/
Iridoides
Limite:
Animals
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Bélgica