Acute toxicity of ochratoxin-A in marine water-reared sea bass (Dicentrarchus labrax L.).
Chemosphere
; 75(7): 878-82, 2009 May.
Article
em En
| MEDLINE
| ID: mdl-19230951
ABSTRACT
The toxic effects of ochratoxin-A (OTA) on sea bass, Dicentrarchus labrax L., have not been previously documented. A flow-through bioassay test system was conducted in two series and a total 180 of adult marine-reared sea bass was used to estimate the acute oral 96 h median lethal concentration (LC(50)) value and behavioral changes of OTA. The data obtained were statistically evaluated using Finney's Probit Analysis Method developed by EPA. The 96 h LC(50) value for adult D. labrax was found to be 277 microg kg(-1)bwt with 95% confidence limits of 244-311 microg kg(-1)bwt. This value was calculated to be 285 microg kg(-1) bwt with Behrens-Karber's method. The two methods were relatively comparable. The acute dietary 96 h LC(50) of OTA is 9.23 mg kg(-1) diet. Additionally, the behavioral changes of sea bass were primarily observed as nervous and respiratory manifestations. We concluded that sea bass is a species highly sensitive to OTA making them a useful experimental model for aquatic mycotoxigenic problems.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poluentes da Água
/
Bass
/
Ocratoxinas
Limite:
Animals
Idioma:
En
Revista:
Chemosphere
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Egito