[Gene therapy for myeloid leukemia].
Nihon Rinsho
; 67(10): 1958-63, 2009 Oct.
Article
em Ja
| MEDLINE
| ID: mdl-19860197
ABSTRACT
Among several immune-gene therapies against myeloid leukemia, "T cell depleted haplo-identical transplantation with HSV-TK gene modified T cell add-back" and "donor lymphocyte infusion using HSV-TK gene modified T cell in patients experiencing recurrence after allogeneic stem cell transplantation" were in advanced stages of clinical development. In this chapter, I will summarize the strategies of gene therapy using HSV-TK gene modified T lymphocyte in allogeneic stem cell transplantation. I will also point out the current situation of other gene therapies such as cytokine gene modified CML-DC and TCR gene modified T lymphocyte against myeloid leukemia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Timidina Quinase
/
Linfócitos T
/
Terapia Genética
/
Leucemia Mieloide
/
Simplexvirus
/
Transplante de Células-Tronco
Limite:
Humans
Idioma:
Ja
Revista:
Nihon Rinsho
Ano de publicação:
2009
Tipo de documento:
Article