Treatment of melanoma-associated retinopathy.
Curr Treat Options Neurol
; 12(1): 54-63, 2010 Jan.
Article
em En
| MEDLINE
| ID: mdl-20842490
ABSTRACT
OPINION STATEMENT Melanoma-associated retinopathy is a rare paraneoplastic disorder that is challenging to diagnose and even more difficult to treat. Because of the rarity of the disease, therapy is based on analysis of case series and case reports. Based on evidence from these reports, first-line therapy is cytoreduction of metastatic disease through metastasectomy, chemotherapy, and radiation. This can be combined with intravenous immunoglobulin. For refractory visual symptoms, additional therapies include systemic corticosteroids and plasmapheresis, but the success of these strategies has been limited. Because of the rarity of the disorder, new therapies should be evaluated and reported in the literature to expand our clinical understanding of this autoimmune disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
Curr Treat Options Neurol
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos