Sterilization of heat-sensitive silicone implant material by low-pressure gas plasma.
Biomed Instrum Technol
; 45(1): 75-9, 2011.
Article
em En
| MEDLINE
| ID: mdl-21322816
ABSTRACT
BACKGROUND:
In recent years, plasma treatment of medical devices and implant materials has gained more and more acceptance. Inactivation of microorganisms by exposure to ultraviolet (UV) radiation produced by plasma discharges and sterilization of medical implants and instruments is one possible application of this technique. The aim of this study was to evaluate the effectiveness of this sterilization technique on silicone implant material.METHODS:
Bacillus atrophaeus spores (10(6) colony-forming units [CFUs]) were sprayed on the surfaces of 12 silicone implant material samples. Four plasma sets with different gas mixtures (argon [Ar], argon-oxygen [ArO(2)], argon-hydrogen [ArH(2)] and argon-nitrogen [ArN(2)]) were tested for their antimicrobial properties. Post-sterilization mechanical testing of the implant material was performed in order to evaluate possible plasma-induced structural damage.RESULTS:
The inductively coupled low-pressure plasma technique can achieve fast and efficient sterilization of silicone implant material without adverse materials effects. All four gas mixtures led to a significant spore reduction, and no structural damage to the implant material could be observed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Próteses e Implantes
/
Esterilização
/
Gases em Plasma
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
Biomed Instrum Technol
Assunto da revista:
ENGENHARIA BIOMEDICA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Alemanha