Lymphangiogenesis and hemangiogenesis: potential targets for therapy.
J Surg Oncol
; 103(6): 489-500, 2011 May 01.
Article
em En
| MEDLINE
| ID: mdl-21480241
ABSTRACT
This review updates historical background from century-old observations on embryonic lymphatic system development through current understanding of the molecular basis of lymphvasculogenesis/lymphangiogenesis ("molecular lymphology"), highlighting similarities and differences with analogous blood vasculature processes. Topics covered include molecular mechanisms in lymphatic development, structural adaptations of the lymphatic vasculature to particulate and cellular transport and trafficking, lymphogenous route of clinical cancer spread, preservation of delineated lymphatic pathways during cancer operations, and anti-lymphangiogenesis in cancer therapy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Inibidores da Angiogênese
/
Linfangiogênese
/
Terapia de Alvo Molecular
/
Neoplasias
/
Neovascularização Patológica
Limite:
Humans
Idioma:
En
Revista:
J Surg Oncol
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos