[Dynamics of functional parameters in different schemes for bronchial asthma therapy: results of the STRELA-ACT multicentre study].
Klin Med (Mosk)
; 89(4): 36-41, 2011.
Article
em Ru
| MEDLINE
| ID: mdl-21932561
ABSTRACT
Different strategies for disease control in real clinical practice are compared in terms of dynamics of functional parameters in patients with persistent bronchial asthma. This prospective multicentre surveillance study was carried out in 19 Russian clinics using the common protocol. The patients were divided in 3 groups in accordance with the changes of basal antiinflammatory therapy during the study period. Group A--stepwise increase in the extent of combined salmoterol/fluticason therapy, group B--long-term stable-dose salmoterol/fluticason therapy, group C--salmoterol/fluticason therapy with gradual decrease of the dose and/or transition to an alternative variant. Statistical analysis using Statistica 6.0 program included data from 543 patients. The results suggest that the two first modalities increased the level of control (ACT test) and improved characteristics of external respiration throughout the study period. Strategy 3 was associated with a decrease in the external respiration function and the level of control.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Broncodilatadores
/
Albuterol
/
Agonistas de Receptores Adrenérgicos beta 2
/
Androstadienos
/
Anti-Inflamatórios
Tipo de estudo:
Clinical_trials
/
Guideline
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Klin Med (Mosk)
Ano de publicação:
2011
Tipo de documento:
Article