Genome, and beyond. Findings from the section on bioinformatics.
Yearb Med Inform
; 6: 156-9, 2011.
Article
em En
| MEDLINE
| ID: mdl-21938342
ABSTRACT
OBJECTIVES:
To summarize current excellent research in the field of bioinformatics, with an emphasis on those that have direct application in the medical domain.METHOD:
Synopsis of the articles selected for the IMIA Yearbook 2011.RESULTS:
The selection process for this yearbook's section on Bioinformatics results in six excellent articles highlighting the continuous progress towards a better understanding of human phenotype. Compared to the selection in Yearbook 2010, several key advancements can be noted. First, year 2010 marked the inaugural use of a complete human genome in a clinical context. This proof-of-principle study represents a large step towards personalized medicine. Second, there is a clear trend to understand diseases beyond the genome level, namely to include environmental and epigenetic information. Third, an innovative framework making use of the web to harness participant-driven genotype-phenotype information sets a new scene for conducting research in an era where social media plays an increasingly important role.CONCLUSIONS:
The current literature showed that all pieces are now present to enable a much more comprehensive understanding of human diseases and traits, beyond the highly focused genetic or genomic studies seen previously.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Biologia Computacional
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Yearb Med Inform
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Suíça