Doxycycline treatment of otosyphilis with hearing loss.
Sex Transm Infect
; 88(3): 177-8, 2012 Apr.
Article
em En
| MEDLINE
| ID: mdl-22287531
ABSTRACT
OBJECTIVES:
The recommended treatment of otosyphilis is intravenous penicillin therapy. The response rate varied between 23% and 31%. This treatment needs hospitalisation and is costly, inconvenient and time consuming. Oral doxycycline was tested for its efficacy in otosyphilis.METHOD:
The authors reviewed 19 patients diagnosed as having otosyphilis with hearing loss at the outpatient unit between 2004 and 2008 by oral doxycycline 400 mg/day for 21 days.RESULTS:
Of those enrolled patients, 12 patients were male and the mean age is 69.4 years. The hearing was improved in nine patients (47.3%) and the audiogram of seven patients (36.8%) showed improvement. There was no serious side effect of doxycycline.CONCLUSION:
The data suggest that doxycycline may be an effective alternate regimen for otosyphilis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Otite
/
Sífilis
/
Doxiciclina
/
Perda Auditiva
/
Antibacterianos
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Sex Transm Infect
Assunto da revista:
DOENCAS SEXUALMENTE TRANSMISSIVEIS
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Tailândia