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Degree of chemical functionalization of carbon nanotubes determines tissue distribution and excretion profile.
Al-Jamal, Khuloud T; Nunes, Antonio; Methven, Laura; Ali-Boucetta, Hanene; Li, Shouping; Toma, Francesca M; Herrero, M Antonia; Al-Jamal, Wafa' T; ten Eikelder, Huub M M; Foster, Julie; Mather, Stephen; Prato, Maurizio; Bianco, Alberto; Kostarelos, Kostas.
Afiliação
  • Al-Jamal KT; Nanomedicine Laboratory, Centre for Drug Delivery Research, UCL School of Pharmacy, University College London, London WC1N 1AX, UK.
Angew Chem Int Ed Engl ; 51(26): 6389-93, 2012 Jun 25.
Article em En | MEDLINE | ID: mdl-22623333
Getting rid of the tubes: An assessment of the retention of functionalized multi-walled carbon nanotubes (MWNTs) in the organs of mice was carried out using single photon emission computed tomography and quantitative scintigraphy (see scheme). Increasing the degree of functionalization on MWNTs enhanced renal clearance, while lower functionalization promoted reticuloendethelial system accumulation.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanotubos de Carbono / Aminas Limite: Animals Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2012 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanotubos de Carbono / Aminas Limite: Animals Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2012 Tipo de documento: Article