Duplex Doppler evaluation of renal allograft dysfunction: Doppler signal quantitation and pathologic correlation.
J Belge Radiol
; 73(6): 475-83, 1990 Nov.
Article
em En
| MEDLINE
| ID: mdl-2277002
ABSTRACT
The value of quantitative duplex Doppler sonography in discriminating the different possible causes of renal transplant dysfunction was prospectively studied in 60 patients during 65 episodes of renal function impairment. Final diagnosis at histology was acute rejection (n 30), acute tubular necrosis (n 4), cyclosporin nephrotoxicity (n 16) and chronic rejection (n 15). Duplex sonography was done the day a percutaneous biopsy was taken and before any therapy was started. Arterial Doppler signals obtained from the segmental, interlobar and arcuate arteries were both morphologically and quantitatively analysed. For quantitative analysis we used the resistive index as proposed by Pourcelot on the one hand, and introduced a variant resistive index on the other hand. Morphological analysis yielded no discriminative value. Comparing both quantitative methods--the resistive index of Pourcelot and the variant resistive index--clearly higher specificities--71% using the variant resistive index, 28% using the resistive index of Pourcelot--for excluding acute rejection from the other possible causes of renal function impairment could be achieved. A nephrectomy was done on 7 patients with severe transplant dysfunction. Microangiographies performed on these nephrectomy specimens were correlated with previous Doppler studies and with histology.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Rim
/
Rim
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Humans
Idioma:
En
Revista:
J Belge Radiol
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
Bélgica