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Pneumococcal serotype distribution among meningitis cases from Togo and Burkina Faso during 2007-2009.
Gessner, Bradford D; Sanou, Oumarou; Drabo, Aly; Tamekloe, Tsidi Agbeko; Yaro, Seydou; Tall, Haoua; Moïsi, Jennifer C; Mueller, Judith E; Njanpop-LaFourcade, Berthe-Marie.
Afiliação
  • Gessner BD; Agence de Medecine Preventive, Paris, France. bgessner@aamp.org
Vaccine ; 30 Suppl 6: G41-5, 2012 Dec 31.
Article em En | MEDLINE | ID: mdl-23228357
We evaluated pneumococcal serotype/group distribution using polymerase chain reaction (PCR) testing on cerebrospinal fluid collected from patients from Burkina Faso and Togo who presented for care during 2007-2009. We identified 282 pneumococcal meningitis cases based on PCR, latex agglutination, or culture, of which 206 underwent serotyping. Serotype 1 was identified for 18% of serotyped cases from patients aged <5 years and 66% of those aged ≥5 years. The 13-valent and 10-valent pneumococcal conjugate vaccines (PCV-13 and PCV-10) contain 53% of serotypes identified among children age <5 years and 76-77% among persons aged ≥5 years. Pneumococcal meningitis was highly seasonal regardless of serotype. Data from this study emphasize the potential usefulness of PCVs among older children and adults.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptococcus pneumoniae / Meningite Pneumocócica Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Africa Idioma: En Revista: Vaccine Ano de publicação: 2012 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptococcus pneumoniae / Meningite Pneumocócica Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Africa Idioma: En Revista: Vaccine Ano de publicação: 2012 Tipo de documento: Article País de afiliação: França