BOX SPLINE BASED 3D TOMOGRAPHIC RECONSTRUCTION OF DIFFUSION PROPAGATORS FROM MRI DATA.

ABSTRACT

This paper introduces a tomographic approach for reconstruction of diffusion propagators, P( r ), in a box spline framework. Box splines are chosen as basis functions for high-order approximation of P( r ) from the diffusion signal. Box splines are a generalization of B-splines to multivariate setting that are particularly useful in the context of tomographic reconstruction. The X-Ray or Radon transform of a (tensor-product B-spline or a non-separable) box spline is a box spline - the space of box splines is closed under the Radon transform.We present synthetic and real multi-shell diffusion-weighted MR data experiments that demonstrate the increased accuracy of P( r ) reconstruction as the order of basis functions is increased.