The oxidative and antioxidative status of simple febrile seizure patients.
J Pak Med Assoc
; 63(5): 594-7, 2013 May.
Article
em En
| MEDLINE
| ID: mdl-23757987
ABSTRACT
OBJECTIVE:
To evaluate the oxidative status following a seizure in children experiencing a simple febrile seizure.METHODS:
The cross-sectional study was conducted at Harran University, Turkey, between January and September 2011. It comprised 32 paediatric patients who, within the preceding 8 hours, had experienced a seizure due to upper respiratory tract infection and had been diagnosed with simple febrile seizure, and 30 healthy children as the control group. Blood was taken from the patients 8 hours after the seizure. Total oxidant level and Total anti-oxidant level were measured according to the Erel technique and the oxidative stress index was calculated. Data was analysed using SPSS 11.5.RESULTS:
The mean values of the total oxidant level and the oxidative stress index of the cases were found to be significantly high compared to the controls and the total anti-oxidant level was found to be significantly low (p < 0.01, p < 0.01, p < 0.03 respectively).CONCLUSION:
The increased total oxidant level and decreased total anti-oxidant level resulting in increased oxidative stress associated with febrile seizure patients may increase the risk of experiencing febrile seizures.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxidantes
/
Convulsões Febris
/
Antioxidantes
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
En
Revista:
J Pak Med Assoc
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Turquia