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Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma.
Rahal, Rami; Frick, Mareike; Romero, Rodrigo; Korn, Joshua M; Kridel, Robert; Chan, Fong Chun; Meissner, Barbara; Bhang, Hyo-eun; Ruddy, Dave; Kauffmann, Audrey; Farsidjani, Ali; Derti, Adnan; Rakiec, Daniel; Naylor, Tara; Pfister, Estelle; Kovats, Steve; Kim, Sunkyu; Dietze, Kerstin; Dörken, Bernd; Steidl, Christian; Tzankov, Alexandar; Hummel, Michael; Monahan, John; Morrissey, Michael P; Fritsch, Christine; Sellers, William R; Cooke, Vesselina G; Gascoyne, Randy D; Lenz, Georg; Stegmeier, Frank.
Afiliação
  • Rahal R; 1] Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA. [2].
  • Frick M; 1] Department of Hematology, Oncology and Tumor Immunology, Molecular Cancer Research Center, Charité-Universitätsmedizin, Berlin, Germany. [2].
  • Romero R; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Korn JM; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Kridel R; Department of Pathology and Experimental Therapeutics, BC Cancer Agency and BC Cancer Research Centre, Vancouver, British Columbia, Canada.
  • Chan FC; Department of Pathology and Experimental Therapeutics, BC Cancer Agency and BC Cancer Research Centre, Vancouver, British Columbia, Canada.
  • Meissner B; Department of Pathology and Experimental Therapeutics, BC Cancer Agency and BC Cancer Research Centre, Vancouver, British Columbia, Canada.
  • Bhang HE; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Ruddy D; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Kauffmann A; Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Farsidjani A; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Derti A; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Rakiec D; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Naylor T; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Pfister E; Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Kovats S; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Kim S; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Dietze K; Department of Hematology, Oncology and Tumor Immunology, Molecular Cancer Research Center, Charité-Universitätsmedizin, Berlin, Germany.
  • Dörken B; Department of Hematology, Oncology and Tumor Immunology, Molecular Cancer Research Center, Charité-Universitätsmedizin, Berlin, Germany.
  • Steidl C; Department of Pathology and Experimental Therapeutics, BC Cancer Agency and BC Cancer Research Centre, Vancouver, British Columbia, Canada.
  • Tzankov A; Institute of Pathology, University Hospital Basel, Basel, Switzerland.
  • Hummel M; Department of Pathology, Charité-Universitätsmedizin, Berlin, Germany.
  • Monahan J; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Morrissey MP; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Fritsch C; Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Sellers WR; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Cooke VG; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Gascoyne RD; Department of Pathology and Experimental Therapeutics, BC Cancer Agency and BC Cancer Research Centre, Vancouver, British Columbia, Canada.
  • Lenz G; 1] Department of Hematology, Oncology and Tumor Immunology, Molecular Cancer Research Center, Charité-Universitätsmedizin, Berlin, Germany. [2].
  • Stegmeier F; 1] Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA. [2].
Nat Med ; 20(1): 87-92, 2014 Jan.
Article em En | MEDLINE | ID: mdl-24362935
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Quinazolinas / Receptores de Antígenos de Linfócitos B / Transdução de Sinais / NF-kappa B / Proteínas Serina-Treonina Quinases / Linfoma de Célula do Manto Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Quinazolinas / Receptores de Antígenos de Linfócitos B / Transdução de Sinais / NF-kappa B / Proteínas Serina-Treonina Quinases / Linfoma de Célula do Manto Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2014 Tipo de documento: Article