Fecal microbiota transplantation inducing remission in Crohn's colitis and the associated changes in fecal microbial profile.
J Clin Gastroenterol
; 48(7): 625-8, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-24667590
ABSTRACT
Inflammatory bowel disease (IBD) is a chronic relapsing disorder of the intestine of unclear etiology. Increasing evidence has pointed to intestinal dysbiosis as a potential factor in a genetically susceptible individual. Fecal microbiota transplantation (FMT) has been used to treat inflammatory bowel disease with variable degrees of success. Herein, we report a patient with Crohn's colitis, previously failing an immunosuppressant, who achieved clinical, endoscopic, and histologic remission after a single fecal microbiota transplantation infusion. We have further characterized the changes in the fecal microbiota associated with this observation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Terapia Biológica
/
Doença de Crohn
/
Fezes
/
Microbiota
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
J Clin Gastroenterol
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Vaticano