Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction.

Fan, Dong; Takawale, Abhijit; Basu, Ratnadeep; Patel, Vaibhav; Lee, Jiwon; Kandalam, Vijay; Wang, Xiuhua; Oudit, Gavin Y; Kassiri, Zamaneh

Fan, Dong; Takawale, Abhijit; Basu, Ratnadeep; Patel, Vaibhav; Lee, Jiwon; Kandalam, Vijay; Wang, Xiuhua; Oudit, Gavin Y; Kassiri, Zamaneh.

Afiliação

Fan D; Department of Physiology Cardiovascular research Centre, Mazankowski Alberta Heart Institute.
Takawale A; Department of Physiology Cardiovascular research Centre, Mazankowski Alberta Heart Institute.
Basu R; Department of Physiology Cardiovascular research Centre, Mazankowski Alberta Heart Institute.
Patel V; Cardiovascular research Centre, Mazankowski Alberta Heart Institute Department of Medicine/Division of Cardiology, University of Alberta, Edmonton AB, Canada.
Lee J; Department of Physiology Cardiovascular research Centre, Mazankowski Alberta Heart Institute.
Kandalam V; Department of Physiology Cardiovascular research Centre, Mazankowski Alberta Heart Institute.
Wang X; Department of Physiology Cardiovascular research Centre, Mazankowski Alberta Heart Institute.
Oudit GY; Cardiovascular research Centre, Mazankowski Alberta Heart Institute Department of Medicine/Division of Cardiology, University of Alberta, Edmonton AB, Canada.
Kassiri Z; Department of Physiology Cardiovascular research Centre, Mazankowski Alberta Heart Institute z.kassiri@ualberta.ca.

Cardiovasc Res ; 103(2): 268-80, 2014 Jul 15.

Article em En | MEDLINE | ID: mdl-24692173

Assuntos

Angiotensina II/metabolismo; Cardiomegalia/enzimologia; Insuficiência Cardíaca Diastólica/enzimologia; Hipertrofia Ventricular Esquerda/genética; Inibidor Tecidual de Metaloproteinase-2/genética; Inibidor Tecidual de Metaloproteinase-3/genética; Animais; Cardiomegalia/genética; Cardiomegalia/fisiopatologia; Cardiomiopatias/genética; Fibrose/genética; Insuficiência Cardíaca Diastólica/genética; Insuficiência Cardíaca Diastólica/fisiopatologia; Hipertrofia Ventricular Esquerda/fisiopatologia; Camundongos Endogâmicos C57BL; Camundongos Knockout; Miocárdio/metabolismo; Remodelação Ventricular/genética

Palavras-chave

Cardiac fibroblast; Diastolic dysfunction; Extracellular matrix; Fibrosis; Hypertrophy; Matricellular proteins; Tissue inhibitor of metalloproteinase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angiotensina II / Hipertrofia Ventricular Esquerda / Cardiomegalia / Inibidor Tecidual de Metaloproteinase-2 / Inibidor Tecidual de Metaloproteinase-3 / Insuficiência Cardíaca Diastólica Limite: Animals Idioma: En Revista: Cardiovasc Res Ano de publicação: 2014 Tipo de documento: Article

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