Avidity of antibodies against infecting pneumococcal serotypes increases with age and severity of disease.
Clin Vaccine Immunol
; 21(6): 904-7, 2014 Jun.
Article
em En
| MEDLINE
| ID: mdl-24759650
ABSTRACT
The incidence of invasive pneumococcal disease (IPD) rises with age. Among adult IPD patients, the avidity of antipneumococcal polysaccharide antibodies against the infecting serotype increased with age and severity of disease, indicating that susceptibility to IPD in the elderly may rather be due to flaws in other aspects of opsonophagocytosis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina G
/
Anticorpos Antibacterianos
/
Afinidade de Anticorpos
Limite:
Humans
Idioma:
En
Revista:
Clin Vaccine Immunol
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
TECNICAS E PROCEDIMENTOS DE LABORATORIO
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Holanda