Reduction of ARNT in myeloid cells causes immune suppression and delayed wound healing.

Scott, Christopher; Bonner, James; Min, Danqing; Boughton, Philip; Stokes, Rebecca; Cha, Kuan Minn; Walters, Stacey N; Maslowski, Kendle; Sierro, Frederic; Grey, Shane T; Twigg, Stephen; McLennan, Susan; Gunton, Jenny E

Scott, Christopher; Bonner, James; Min, Danqing; Boughton, Philip; Stokes, Rebecca; Cha, Kuan Minn; Walters, Stacey N; Maslowski, Kendle; Sierro, Frederic; Grey, Shane T; Twigg, Stephen; McLennan, Susan; Gunton, Jenny E.

Afiliação

Scott C; Diabetes and Transcription Factors Group, Department of Immunology and Inflammation, Garvan Institute of Medical Research, Sydney, New South Wales, Australia; Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia;
Bonner J; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia;
Min D; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia;
Boughton P; St. George Clinical School, St. George Hospital, Kogarah, New South Wales, Australia; Department of Biomedical Engineering, University of Sydney, Sydney, New South Wales, Australia;
Stokes R; Diabetes and Transcription Factors Group, Department of Immunology and Inflammation, Garvan Institute of Medical Research, Sydney, New South Wales, Australia;
Cha KM; Diabetes and Transcription Factors Group, Department of Immunology and Inflammation, Garvan Institute of Medical Research, Sydney, New South Wales, Australia;
Walters SN; Department of Immunology and Inflammation, Garvan Institute of Medical Research, Sydney, New South Wales, Australia;
Maslowski K; Department of Biochemistry, University of Lausanne, Lausanne, Switzerland;
Sierro F; Liver Immunology, Centenary Institute, Sydney, New South Wales, Australia;
Grey ST; Department of Immunology and Inflammation, Garvan Institute of Medical Research, Sydney, New South Wales, Australia;
Twigg S; Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia;
McLennan S; Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia;
Gunton JE; Diabetes and Transcription Factors Group, Department of Immunology and Inflammation, Garvan Institute of Medical Research, Sydney, New South Wales, Australia; Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia; St. Vincent's Clinical School, University of New South Wales,

Am J Physiol Cell Physiol ; 307(4): C349-57, 2014 Aug 15.

Article em En | MEDLINE | ID: mdl-24990649

Assuntos

Translocador Nuclear Receptor Aril Hidrocarboneto/deficiência; Translocador Nuclear Receptor Aril Hidrocarboneto/metabolismo; Imunidade Inata; Hospedeiro Imunocomprometido; Células Mieloides/metabolismo; Tolerância ao Transplante; Cicatrização; Idoso; Animais; Translocador Nuclear Receptor Aril Hidrocarboneto/genética; Estudos de Casos e Controles; Células Cultivadas; Citocinas/genética; Citocinas/metabolismo; Desferroxamina/farmacologia; Dermatite/genética; Dermatite/imunologia; Dermatite/metabolismo; Dermatite/patologia; Complicações do Diabetes/genética; Complicações do Diabetes/imunologia; Complicações do Diabetes/metabolismo; Complicações do Diabetes/patologia; Diabetes Mellitus Experimental/genética; Diabetes Mellitus Experimental/imunologia; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Experimental/patologia; Feminino; Regulação da Expressão Gênica; Genótipo; Sobrevivência de Enxerto; Humanos; Imunidade Inata/genética; Hospedeiro Imunocomprometido/genética; Mediadores da Inflamação/metabolismo; Integrases/genética; Ativação de Macrófagos; Macrófagos/imunologia; Macrófagos/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Camundongos Knockout; Camundongos Transgênicos; Pessoa de Meia-Idade; Monócitos/imunologia; Monócitos/metabolismo; Muramidase/genética; Células Mieloides/efeitos dos fármacos; Células Mieloides/imunologia; Fenótipo; RNA Mensageiro/metabolismo; Pele/imunologia; Pele/metabolismo; Pele/patologia; Transplante de Pele

Palavras-chave

aryl hydrocarbon receptor nuclear translocator; deferoxamine; hypoxia-inducible factor-1α

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cicatrização / Hospedeiro Imunocomprometido / Células Mieloides / Tolerância ao Transplante / Translocador Nuclear Receptor Aril Hidrocarboneto / Imunidade Inata Tipo de estudo: Etiology_studies / Observational_studies Idioma: En Revista: Am J Physiol Cell Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2014 Tipo de documento: Article

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