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Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.
Suh, Jae Myoung; Jonker, Johan W; Ahmadian, Maryam; Goetz, Regina; Lackey, Denise; Osborn, Olivia; Huang, Zhifeng; Liu, Weilin; Yoshihara, Eiji; van Dijk, Theo H; Havinga, Rick; Fan, Weiwei; Yin, Yun-Qiang; Yu, Ruth T; Liddle, Christopher; Atkins, Annette R; Olefsky, Jerrold M; Mohammadi, Moosa; Downes, Michael; Evans, Ronald M.
Afiliação
  • Suh JM; 1] Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA [2].
  • Jonker JW; 1] Center for Liver, Digestive and Metabolic Diseases, Departments of Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands [2].
  • Ahmadian M; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
  • Goetz R; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York 10016, USA.
  • Lackey D; Department of Medicine, Division of Endocrinology and Metabolism, University of California at San Diego, La Jolla, California 92093, USA.
  • Osborn O; Department of Medicine, Division of Endocrinology and Metabolism, University of California at San Diego, La Jolla, California 92093, USA.
  • Huang Z; 1] Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York 10016, USA [2] School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
  • Liu W; Center for Liver, Digestive and Metabolic Diseases, Departments of Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Yoshihara E; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
  • van Dijk TH; Center for Liver, Digestive and Metabolic Diseases, Departments of Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Havinga R; Center for Liver, Digestive and Metabolic Diseases, Departments of Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Fan W; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
  • Yin YQ; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
  • Yu RT; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
  • Liddle C; The Storr Liver Unit, Westmead Millennium Institute and University of Sydney, Westmead Hospital, Westmead, New South Wales 2145, Australia.
  • Atkins AR; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
  • Olefsky JM; Department of Medicine, Division of Endocrinology and Metabolism, University of California at San Diego, La Jolla, California 92093, USA.
  • Mohammadi M; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York 10016, USA.
  • Downes M; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
  • Evans RM; 1] Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA [2] Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
Nature ; 513(7518): 436-9, 2014 Sep 18.
Article em En | MEDLINE | ID: mdl-25043058
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator 1 de Crescimento de Fibroblastos / Glucose / Insulina Limite: Animals / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator 1 de Crescimento de Fibroblastos / Glucose / Insulina Limite: Animals / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2014 Tipo de documento: Article