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eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies.
Boussemart, Lise; Malka-Mahieu, Hélène; Girault, Isabelle; Allard, Delphine; Hemmingsson, Oskar; Tomasic, Gorana; Thomas, Marina; Basmadjian, Christine; Ribeiro, Nigel; Thuaud, Frédéric; Mateus, Christina; Routier, Emilie; Kamsu-Kom, Nyam; Agoussi, Sandrine; Eggermont, Alexander M; Désaubry, Laurent; Robert, Caroline; Vagner, Stéphan.
Afiliação
  • Boussemart L; 1] Inserm UMR981, Villejuif F-94805, France [2] Université Paris-Sud XI, Kremlin-Bicêtre F-94276, France [3] Gustave Roussy, Dermato-Oncology, Villejuif F-94805, France [4].
  • Malka-Mahieu H; 1] Inserm UMR981, Villejuif F-94805, France [2] Université Paris-Sud XI, Kremlin-Bicêtre F-94276, France [3].
  • Girault I; 1] Inserm UMR981, Villejuif F-94805, France [2].
  • Allard D; Inserm UMR981, Villejuif F-94805, France.
  • Hemmingsson O; 1] Inserm UMR981, Villejuif F-94805, France [2] Department of Surgical and Perioperative Sciences, Umeå University, Umeå SE-90187, Sweden (O.H.); CNRS UMR3348, Institut Curie, Orsay F-91405, France (S.V.).
  • Tomasic G; Gustave Roussy, Pathology Department, Villejuif F-94805, France.
  • Thomas M; Gustave Roussy, Dermato-Oncology, Villejuif F-94805, France.
  • Basmadjian C; CNRS-Strasbourg University, UMR7200, Illkirch F-67400, France.
  • Ribeiro N; CNRS-Strasbourg University, UMR7200, Illkirch F-67400, France.
  • Thuaud F; CNRS-Strasbourg University, UMR7200, Illkirch F-67400, France.
  • Mateus C; Gustave Roussy, Dermato-Oncology, Villejuif F-94805, France.
  • Routier E; Gustave Roussy, Dermato-Oncology, Villejuif F-94805, France.
  • Kamsu-Kom N; Inserm UMR981, Villejuif F-94805, France.
  • Agoussi S; Inserm UMR981, Villejuif F-94805, France.
  • Eggermont AM; 1] Université Paris-Sud XI, Kremlin-Bicêtre F-94276, France [2] Gustave Roussy, Dermato-Oncology, Villejuif F-94805, France.
  • Désaubry L; CNRS-Strasbourg University, UMR7200, Illkirch F-67400, France.
  • Robert C; 1] Inserm UMR981, Villejuif F-94805, France [2] Université Paris-Sud XI, Kremlin-Bicêtre F-94276, France [3] Gustave Roussy, Dermato-Oncology, Villejuif F-94805, France.
  • Vagner S; 1] Inserm UMR981, Villejuif F-94805, France [2] Université Paris-Sud XI, Kremlin-Bicêtre F-94276, France [3] Gustave Roussy, Dermato-Oncology, Villejuif F-94805, France [4] Department of Surgical and Perioperative Sciences, Umeå University, Umeå SE-90187, Sweden (O.H.); CNRS UMR3348, Institut Curie,
Nature ; 513(7516): 105-9, 2014 Sep 04.
Article em En | MEDLINE | ID: mdl-25079330
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Quinases de Proteína Quinase Ativadas por Mitógeno / Fator de Iniciação 4F em Eucariotos / Proteínas Proto-Oncogênicas B-raf / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Nature Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Quinases de Proteína Quinase Ativadas por Mitógeno / Fator de Iniciação 4F em Eucariotos / Proteínas Proto-Oncogênicas B-raf / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Nature Ano de publicação: 2014 Tipo de documento: Article