An efficient three-component synthesis of highly functionalized tetrahydroacenaphtho[1,2-b]indolone derivatives catalyzed by L-proline.
Mol Divers
; 18(4): 727-36, 2014 Nov.
Article
em En
| MEDLINE
| ID: mdl-25151274
ABSTRACT
An efficient and diastereoselective synthetic procedure for highly functionalized tetrahydroacenaphtho[1,2-b]indolone derivatives was successfully developed by the three-component reaction of acenaphthequinone, enaminones, and barbituric acid in the presence of a catalytic amount of L-proline. This method has the advantages of convenient operation, excellent yields, mild reaction conditions, and environmental friendliness.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prolina
/
Técnicas de Química Combinatória
/
Indóis
Idioma:
En
Revista:
Mol Divers
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2014
Tipo de documento:
Article