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SET7/9 methylation of the pluripotency factor LIN28A is a nucleolar localization mechanism that blocks let-7 biogenesis in human ESCs.
Kim, Seung-Kyoon; Lee, Hosuk; Han, Kyumin; Kim, Sang Cheol; Choi, Yoonjung; Park, Sang-Wook; Bak, Geunu; Lee, Younghoon; Choi, Jung Kyoon; Kim, Tae-Kyung; Han, Yong-Mahn; Lee, Daeyoup.
Afiliação
  • Kim SK; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
  • Lee H; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
  • Han K; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
  • Kim SC; Samsung Genome Institute, Samsung Medical Center, Seoul 135-710, Republic of Korea.
  • Choi Y; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
  • Park SW; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
  • Bak G; Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
  • Lee Y; Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
  • Choi JK; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
  • Kim TK; Department of Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.
  • Han YM; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea. Electronic address: ymhan@kaist.ac.kr.
  • Lee D; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea. Electronic address: daeyoup@kaist.ac.kr.
Cell Stem Cell ; 15(6): 735-49, 2014 Dec 04.
Article em En | MEDLINE | ID: mdl-25479749

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nucléolo Celular / Proteínas de Ligação a RNA / Células-Tronco Pluripotentes / MicroRNAs / Células-Tronco Embrionárias Limite: Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nucléolo Celular / Proteínas de Ligação a RNA / Células-Tronco Pluripotentes / MicroRNAs / Células-Tronco Embrionárias Limite: Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2014 Tipo de documento: Article