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The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.
Laptenko, Oleg; Shiff, Idit; Freed-Pastor, Will; Zupnick, Andrew; Mattia, Melissa; Freulich, Ella; Shamir, Inbal; Kadouri, Noam; Kahan, Tamar; Manfredi, James; Simon, Itamar; Prives, Carol.
Afiliação
  • Laptenko O; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Shiff I; Department of Microbiology and Molecular Genetics, Hebrew University Medical School, IMRIC, Jerusalem 91120, Israel.
  • Freed-Pastor W; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Zupnick A; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Mattia M; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Freulich E; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Shamir I; Department of Microbiology and Molecular Genetics, Hebrew University Medical School, IMRIC, Jerusalem 91120, Israel.
  • Kadouri N; Department of Microbiology and Molecular Genetics, Hebrew University Medical School, IMRIC, Jerusalem 91120, Israel.
  • Kahan T; Department of Microbiology and Molecular Genetics, Hebrew University Medical School, IMRIC, Jerusalem 91120, Israel.
  • Manfredi J; Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY 10029, USA.
  • Simon I; Department of Microbiology and Molecular Genetics, Hebrew University Medical School, IMRIC, Jerusalem 91120, Israel. Electronic address: itamarsi@ekmd.huji.ac.il.
  • Prives C; Department of Biological Sciences, Columbia University, New York, NY 10027, USA. Electronic address: clp3@columbia.edu.
Mol Cell ; 57(6): 1034-1046, 2015 Mar 19.
Article em En | MEDLINE | ID: mdl-25794615
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Proteína Supressora de Tumor p53 Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Proteína Supressora de Tumor p53 Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos