Sesquiterpenes, flavonoids, shikimic acid derivatives and pyrrolizidine alkaloids from Senecio kingii Hook.
Phytochemistry
; 117: 245-253, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-26101146
ABSTRACT
Twenty-four compounds including eleven eremophilanolides (1-11), one eremophilane (13), five shikimic acid derivatives (14-18), six flavonoids (19-24), and the macrocyclic unsaturated pyrrolizidine alkaloid integerrimine (25) were isolated from Senecio kingii, an endemic species from the Magallanes Region (Chile). Compounds 3, 5, 6, 8-11 and 13-18 have not been previously reported as natural products. Their molecular structures were determined by NMR spectroscopic analysis and comparison with published NMR data. An X-ray-analysis of compound 3 has been performed. Their insecticidal and antifungal activities were tested, being compound 3 the strongest insect antifeedant. Compounds 6, 9 and 18 were moderate antifungals.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alcaloides de Pirrolizidina
/
Senécio
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Sesquiterpenos
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Flavonoides
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Inseticidas
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Antifúngicos
Limite:
Animals
País/Região como assunto:
America do sul
/
Chile
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Espanha