The genetic variant rs4073 AâT of the Interleukin-8 promoter region is associated with the earlier onset of exudative age-related macular degeneration.

Hautamäki, Asta; Seitsonen, Sanna; Holopainen, Juha M; Moilanen, Jukka A; Kivioja, Jarno; Onkamo, Päivi; Järvelä, Irma; Immonen, Ilkka

The genetic variant rs4073 AâT of the Interleukin-8 promoter region is associated with the earlier onset of exudative age-related macular degeneration.

Hautamäki, Asta; Seitsonen, Sanna; Holopainen, Juha M; Moilanen, Jukka A; Kivioja, Jarno; Onkamo, Päivi; Järvelä, Irma; Immonen, Ilkka.

Afiliação

Hautamäki A; Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Seitsonen S; Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Holopainen JM; Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Moilanen JA; Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Kivioja J; Department of Medical Genetics, University of Helsinki, Helsinki, Finland.
Onkamo P; Department of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Järvelä I; Department of Medical Genetics, University of Helsinki, Helsinki, Finland.
Immonen I; Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Acta Ophthalmol ; 93(8): 726-33, 2015 Dec.

Article em En | MEDLINE | ID: mdl-26154559

Assuntos

Interleucina-8/genética; Polimorfismo de Nucleotídeo Único; Regiões Promotoras Genéticas/genética; Degeneração Macular Exsudativa/genética; Idoso; Idoso de 80 Anos ou mais; Complemento C3/genética; Fator H do Complemento/genética; Feminino; Genótipo; Atrofia Geográfica/genética; Humanos; Masculino; Pessoa de Meia-Idade; Reação em Cadeia da Polimerase; Estudos Retrospectivos; Fatores de Risco; Fumar/genética

Palavras-chave

exudative age-related macular degeneration; genetic associations; interleukin-8; single nucleotide polymorphism

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-8 / Regiões Promotoras Genéticas / Polimorfismo de Nucleotídeo Único / Degeneração Macular Exsudativa Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Ophthalmol Assunto da revista: OFTALMOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Finlândia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google